Is Methylene Blue Safe? Risks, Side Effects, and Dosage Guide

Methylene blue is becoming a popular biohacking supplement, but is it safe? In this guide, we’ll break down the potential risks, side effects, and proper dosage for safe use.

Is Methylene Blue Safe?

In low doses, methylene blue is generally considered safe and well-tolerated. It has been used in medicine for over a century and has even been approved for certain medical treatments.

However, higher doses or improper use may lead to side effects and toxicity.

Common Side Effects of Methylene Blue

🔹 Blue Urine & Skin Tint – Harmless but noticeable
🔹 Digestive Issues – Mild nausea or stomach discomfort
🔹 Headaches – Due to increased oxygen use in the brain
🔹 Insomnia – Best taken earlier in the day

Who Should Avoid Methylene Blue?

🚫 People on SSRIs or MAOIs – Can cause serotonin syndrome
🚫 Pregnant or breastfeeding women – Not enough research available
🚫 Individuals with G6PD deficiency – Higher risk of side effects

How to Take Methylene Blue Safely

  • Start with a low dose (0.5–1mg per kg of body weight)
  • Dilute in water to avoid staining
  • Avoid combining with antidepressants without medical advice
  • Monitor your body’s reaction and adjust dosage accordingly

Conclusion

Methylene blue is generally safe in low doses and offers numerous health benefits. However, proper dosing and precautions are essential to avoid side effects. Always consult a healthcare professional before starting.